Spontaneous ruptures in Descemet’s membrane can result in interlamellar fluid or even a corneal cyst. Spontaneous perforation is rare, although perforation can occur easily with minor trauma. Vessels transverse the furrow and pass beyond it. A yellow line of lipid deposits appears at the leading edge of the pannus (central edge of the furrow). The central wall is steep, and the peripheral wall slopes gradually. The thinning spreads circumferentially, rarely involves the inferior limbus, and leaves the epithelium intact.
Opacification is followed by the development of a peripheral, superficial, fine vascular pannus, which progresses over the years to include subepithelial opacity at the advancing edge, without the overlying edge characteristic of Mooren’s ulcer. Degeneration typically begins superiorly with mild, punctuate subepithelial and/or anterior stromal opacities and leaves a clear area between the opacities and the limbus. Degeneration may lead to a high degree of against-the-rule or oblique astigmatism.Ĭorneal thinning can be localized or involve extensive proportions of the peripheral cornea.
It causes a slowly progressive non-inflammatory, unilateral or asymmetrically bilateral peripheral corneal thinning and is associated with corneal neovascularization, opacification and lipid deposition. Terrien’s marginal degeneration is an uncommon but distinct variety of marginal thinning of the cornea. Peripheral degenerations of cornea, ICD-9 371.48.
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